Health examinations
鎳 Nickel (Ni)
Nickel (Ni)

*Nickel is a metallic element widely used in industry. Although the body's requirement for nickel is minimal, it plays a crucial role in several physiological functions, including:
-Role as an essential trace element: While the body's demand for nickel is extremely low, it is important for certain enzyme functions, such as urease and superoxide dismutase (SOD).
-Influence on iron metabolism: Nickel may play a role in iron metabolism, affecting red blood cell formation and hemoglobin synthesis. A deficiency in nickel may lead to anemia or growth retardation.
-Participation in gene expression and enzyme activity regulation: Nickel may influence the activity of certain enzymes, such as RNA polymerase, and contribute to DNA and RNA synthesis, impacting cell proliferation and growth.
-Effect on hormone regulation: Research suggests that nickel may affect the metabolism of certain hormones, such as adrenaline and thyroid hormones, indirectly influencing energy metabolism and physiological functions.

*Although nickel is beneficial to organisms in trace amounts, excessive intake or prolonged exposure may lead to toxic effects. Therefore, when working in environments with long-term or high levels of exposure, proper personal protective measures should be taken.

*Normal Range
Blood Nickel Levels:<30 μg/g CRE (may vary depending on testing methods and exposure conditions)

*Health Risks of Excessive Nickel Exposure
-Allergic Reactions:
Prolonged exposure to nickel can cause skin allergies such as contact dermatitis.
-Respiratory System:
Inhalation of nickel dust or vapors can irritate the respiratory tract and may lead to chronic lung conditions.
-Cancer Risk:
Long-term exposure to high concentrations of nickel increases the risk of lung cancer and nasal cancer.
-Kidney Damage:
Prolonged nickel exposure can harm the kidneys, impairing their function.

*How to Reduce Nickel Exposure?
-Avoid Contact:
Limit exposure to nickel-containing items like jewelry and coins, especially for individuals with nickel allergies.
-Use Protective Equipment:
In industrial settings, wear protective gear to prevent inhalation of nickel dust or vapors.
-Practice Good Hygiene:
Wash hands frequently to minimize nickel absorption into the body.
-Maintain a Healthy Diet:
Strengthen the immune system through a balanced diet to reduce the likelihood of allergic reactions.

*Conclusion
While small amounts of nickel are generally harmless, excessive exposure can lead to allergies, respiratory issues, kidney damage, or even cancer. By limiting contact, using protective measures, and maintaining good hygiene, you can effectively reduce the health risks associated with nickel exposure.