Health examinations
B型肝炎病毒e抗體 Anti-HBe
Hepatitis B Virus e Antibody (Anti-HBe)

*What is Anti-HBe?
Hepatitis B virus e antibody (Anti-HBe) is an immune response to the hepatitis B virus e antigen (HBeAg). It appears during the recovery phase of hepatitis B infection or when chronic hepatitis B activity decreases. Anti-HBe positivity usually indicates reduced viral replication, a favorable clinical prognosis, and decreased infectivity and transmissibility of the virus.

*Normal Range
Negative (Nonreactive) < 1.0 S/CO: No detectable Anti-HBe. This may indicate ongoing viral replication with HBeAg positivity or that the individual has not been infected with HBV.
Positive (Reactive) ≥ 1.0 S/CO: Anti-HBe is present, which usually suggests reduced viral replication and lower infectivity.

*Significance of Anti-HBe Positivity
-Recovery or Chronic Immune Response:
A positive Anti-HBe result typically indicates that a hepatitis B patient is in the recovery phase or that chronic hepatitis B activity has decreased. This suggests reduced viral replication and lower transmissibility.
-A Favorable Prognostic Marker for Chronic Hepatitis B:
In chronic hepatitis B patients, Anti-HBe positivity often signifies that the disease is stabilizing, with low viral load and improved liver function.

*Health Recommendations
-Regular Monitoring:
If Anti-HBe is positive, continued regular monitoring of liver function and viral load is recommended to track disease progression.
-Treatment Management:
In chronic hepatitis B patients, antiviral therapy can help achieve Anti-HBe positivity, which reduces the risk of disease progression and transmission.

*Conclusion
A positive Anti-HBe result usually indicates reduced viral activity or recovery. It is a marker of lower infectivity and a favorable prognosis, often persisting for many years. For chronic hepatitis B patients, Anti-HBe positivity suggests disease stabilization. Regular check-ups and monitoring play a crucial role in effectively managing the condition.