同半胱胺酸 Homocystine
Homocysteine: A Marker for Cardiovascular Risk
*Homocysteine is a sulfur-containing amino acid produced during metabolic processes. Elevated levels are associated with increased risks of cardiovascular diseases, thrombosis, and stroke.
*Normal Range
Male：5.46~16.2 umol/L
Female：4.44~13.56 umol/L
*Causes of Elevated Homocysteine
-Vitamin Deficiency:
Lack of folate, vitamin B6, or B12 disrupts homocysteine metabolism, leading to elevated levels.
-Genetic Factors:
Mutations in genes such as MTHFR can predispose individuals to higher homocysteine levels.
-Cardiovascular Diseases:
High homocysteine is linked to atherosclerosis, heart disease, and stroke.
-Kidney Disease:
Chronic kidney disease or uremia often results in elevated homocysteine levels.
*Risks of High Homocysteine
-Cardiovascular Diseases:
Elevated levels can damage vascular endothelium, accelerating atherosclerosis.
-Thrombosis:
Promotes blood clot formation, increasing the risk of venous thrombosis.
-Stroke:
Chronic high homocysteine significantly increases stroke risk.
*How to Lower Homocysteine Levels
-Vitamin Supplementation:
Folate, vitamin B6, and B12 aid in homocysteine metabolism and help reduce its levels.
-Balanced Diet:
Include foods rich in folate and B vitamins (e.g., leafy green vegetables, whole grains, legumes, and animal liver).
-Regular Exercise:
Physical activity supports cardiovascular health and indirectly lowers homocysteine levels.
-Quit Smoking and Limit Alcohol:
Smoking and excessive alcohol consumption impair cardiovascular health and homocysteine metabolism.
*Conclusion
Homocysteine is a critical marker for cardiovascular risk. Elevated levels warrant early intervention. Maintaining a balanced diet, supplementing essential vitamins, regular exercise, and avoiding smoking and excessive alcohol intake can effectively keep homocysteine within a healthy range, reducing the risk of cardiovascular complications.
*Homocysteine is a sulfur-containing amino acid produced during metabolic processes. Elevated levels are associated with increased risks of cardiovascular diseases, thrombosis, and stroke.
*Normal Range
Male：5.46~16.2 umol/L
Female：4.44~13.56 umol/L
*Causes of Elevated Homocysteine
-Vitamin Deficiency:
Lack of folate, vitamin B6, or B12 disrupts homocysteine metabolism, leading to elevated levels.
-Genetic Factors:
Mutations in genes such as MTHFR can predispose individuals to higher homocysteine levels.
-Cardiovascular Diseases:
High homocysteine is linked to atherosclerosis, heart disease, and stroke.
-Kidney Disease:
Chronic kidney disease or uremia often results in elevated homocysteine levels.
*Risks of High Homocysteine
-Cardiovascular Diseases:
Elevated levels can damage vascular endothelium, accelerating atherosclerosis.
-Thrombosis:
Promotes blood clot formation, increasing the risk of venous thrombosis.
-Stroke:
Chronic high homocysteine significantly increases stroke risk.
*How to Lower Homocysteine Levels
-Vitamin Supplementation:
Folate, vitamin B6, and B12 aid in homocysteine metabolism and help reduce its levels.
-Balanced Diet:
Include foods rich in folate and B vitamins (e.g., leafy green vegetables, whole grains, legumes, and animal liver).
-Regular Exercise:
Physical activity supports cardiovascular health and indirectly lowers homocysteine levels.
-Quit Smoking and Limit Alcohol:
Smoking and excessive alcohol consumption impair cardiovascular health and homocysteine metabolism.
*Conclusion
Homocysteine is a critical marker for cardiovascular risk. Elevated levels warrant early intervention. Maintaining a balanced diet, supplementing essential vitamins, regular exercise, and avoiding smoking and excessive alcohol intake can effectively keep homocysteine within a healthy range, reducing the risk of cardiovascular complications.